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. This creates significant opportunities to accelerate research efforts and deepen our understanding of resistance mechanisms. AMR research encompasses, but is not limited to, the discovery and development of new
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using size-exclusion chromatography (SEC) and/or engineering. Practical experience in cellular assays. Practical experience of functional evaluation of proteins/mechanisms. Practical experience of flow
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identity and extracellular signaling, but how cell types, signaling mechanisms, and transcription factors jointly determine tissue structure is incompletely understood. The Koplev lab is recruiting
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focuses particularly on understanding how the tumor microenvironment (TME) undergoes architectural remodeling – including changes in extracellular matrix composition, tissue mechanics, and spatial
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) Experimentally test hypotheses on candidate mechanisms leading to female sex ratio bias (e.g., meiotic drive with restorers) using existing and new crosses. (3) Establish the genetic underpinnings of sex ratio
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-cohort and perturbation datasets, the work aims to uncover isoform-level regulatory mechanisms and guide the development of next-generation RNA therapeutics with improved specificity and reduced off-target