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focuses on the structural and dynamic characterization of intrinsically disordered and multidomain proteins involved in major biological processes, combining experimental biophysics approaches (SAXS, NMR
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progression, as well as in response to treatment, and will assess their potential as new therapeutic targets. Activities: •Cell culture: isolation, expansion and maintenance of glioblastoma stem cells and
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pombe. We hypothesise that rapid adaptive responses involve post-translational modifications (PTMs) of cohesin, a complex essential for chromatin structuring. These PTMs could remodel chromatin
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remodelling events, thereby generating the mechanical forces required for its motility. This motility also relies on the dynamics of adhesion structures to the extracellular matrix. Genetic evidence
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, nanoparticle structure, and function. This position is located within an area subject to the French Protection of Scientific and Technical Potential (PPST) regulations. Consequently, in accordance with French
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at the IPCMS (Institute of Physics and Chemistry of Materials of Strasbourg), which investigates the electronic, optical, and magnetic properties of atomic-scale structures. The research will be carried out
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development remains limited by the difficulty in obtaining crystals with high structural quality, specifically with a stacking fault density below 500/cm². The Travelling Solvent Method (TSM), which uses a
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Polytechnique de Paris in the field of physics. In vertebrates, the anatomy and structure of the brain are established during early development, and any abnormalities during these crucial stages can lead to
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Belfort-Sévenans. The primary objective of this doctoral thesis is to reconsider current models related to economic structures and the connectivity of human communities during the early Middle Ages (6th
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of physical faults, sensor drift, and anomalies affecting measurement and communication systems, whether intentional or not. • Construction of databases dedicated to anomaly detection and fault diagnosis. 2