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mice and humans for analysis Flow cytometry and fluorescence-activated cell sorting (FACS) ELISA and other protein quantification assays Cell culture of hematopoietic stem cells, mesenchymal stem
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biology of glioblastoma stem cells. Proteomic approaches have identified several surface proteins that are overexpressed in glioblastoma stem cells compared with non-tumour cells, and whose role in
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the fundamental principles that allow genome duplication to scale across the extraordinary diversity of mammalian cells, from rapidly proliferating stem cells to differentiated and polyploid tissues
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immunotherapeutic approaches ( https://www.guermonprezlab.org ). There is strong evidence that some populations of CD8+ cells like tissue resident memory-like (TRMs) or poorly differentiated stem-like T
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become: effector cells, regulatory cells, or long-lived stem-like TCF1⁺ cells that sustain immunity. How DCs direct these outcomes is still poorly understood. Our lab studies human DC biology and
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postdocs always work collaboratively together in teams towards common goals to ensure that no one is left to work alone on a project. Our labs are located in the Center for stem cell medicine ( https
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interested in studying the role of cell-biomaterial interactions that 1) mediate differentiation of induced pluripotent stem cells into cardiovascular lineages, and 2) biomaterials that mediate
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in human pluripotent stem cell culture, precision CRISPR-Cas9 genome engineering, stem cell differentiation, and the generation of stem cell-derived pancreatic beta cells and islets. The facility
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treatment of some leukaemias, but current therapies remain expensive, complex to manufacture and tailored to individual patients. Differentiation of human pluripotent stem cells (PSCs) offers a promising
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Yale School of Medicine - Department of Genetics | New Haven, Connecticut | United States | 7 days ago
, uterus/embryo), mammary gland, brain, bone marrow, skin or tumours. No prior lung experience is required. We study how stem cells change identity after injury and how this plasticity can lead to