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Field
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, organogenesis, stem cells and regenerative medicine. Our studies seek to define molecular mechanisms governing both normal and abnormal craniofacial development, providing scientific rationales for future
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, Irvine in the laboratory of Dr. Mehboob Hussain. The successful candidate will explore regulation of metabolism in multiple tissues using in in vivo mouse models as well as human (stem) cell systems and
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injury. Using human stem cell-derived neural models, cerebral organoids, animal models, electrophysiology, mouse behavioral assays, and multi-omics approaches, the lab focuses on mitochondrial dysfunction
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vitro cell culture of stems cells and primary lymphocytes and should also have extensive experience with genetic editing techniques, regulatory T-cell phenotyping and functional assays, as well as in vivo
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. The position is supported by funding from the Burroughs Wellcome Fund and UCLA Start-up funding. Candidates with a background in genomic data analysis, stem cell biology, metabolism, and/or related disciplines
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. The group explores genetic causes of neurological disorders and aim to develop therapies for these conditions with a high complementary approach, ranging from stem cell modelling to functional genomic
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-on experience in gastrointestinal physiology, immunology, inflammatory diseases, or stem cell biology. Experience in molecular and cell biology, flow cytometry, FACS cell isolation and analysis. Experience
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the frontiers of developmental biology and disease modeling. The laboratory integrates stem-cell biology, fluorescence imaging, bioinformatics, and advanced nano- and micro-engineering to decode organogenesis and
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disorders using brain organoids derived from human induced pluripotent stem cells (hiPSCs). The Meng lab integrates brain organoid models with CRISPR-Cas9-based genetic screening, antisense oligonucleotide
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. This is an exceptional opportunity for a motivated postdoctoral scientist to contribute to a highly innovative Alzheimer’s Research UK-funded programme at the interface of stem-cell biology, neuroimmunology