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cells including macrophages). - Modelling of CKD-like vascular injury in 3D vascular organoids derived from induced pluripotent stem cells (iPSCs), exposed to phosphate, uremic toxins and pro-inflammatory
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, neurodegeneration, advanced microscopy, stem cell biology, and cell biology. The project will leverage state-of-the-art imaging facilities and established human iPSC-derived models of Alzheimer's disease. The work is
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neural stem cell (NSC) niche. Recent studies have revealed key aspects of human rhombic lip (hRL) organization and shown that defects in its development underlie several human syndromes. These findings
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