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experimental studies with insights from human populations. We use single-cell and spatial genomics, epigenomic profiling, microbiome analysis, and large-scale human datasets to uncover biological principles in
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. To tackle these questions, they combine in vivo CRISPR screening with single-cell multi-omics, spatial genomics, and chemical biology tools. Their work is deeply collaborative, both within the lab and across
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strategies to restore tissue function and promote healthy aging. By integrating molecular genetics, quantitative imaging, single-cell and spatial genomics, bioengineering, and engineered extracellular matrix
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of neurons control the spatial and temporal structure of cortical activity. Towards this goal, they use in vivo and in vitro electrophysiological, imaging, and anatomical techniques as well as behavioral
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and custom annotation software Good spatial visualization skills and hand-eye coordination. Collect relevant data from multidimensional images and videos Review/correct automatically or manually
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they continue to investigate. Approaches include genetics, spatial genomics, single-molecule biophysics, super-resolution imaging, computational modeling, and structural studies including X-ray
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, especially viruses and bacteria evolving within their hosts and solid tumors progressing to malignancy. In particular, they are characterizing how spatial organization shapes these evolutionary outcomes and
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Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. TLDR: Build the data backbone for the next era of AI-powered spatial
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, reproduction, and development. They use cutting-edge single-cell, spatial, in vitro, and surgical approaches in multiple model species and in human organoids to investigate the uterine endometrium and maternal