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software, analytical platform, chemistry and microbiology laboratories. **Main contacts (CNRS internal and external network):** JH Renault (ICMR), Véronique Eparvier (ICSN), Maria Halabalaki (NPMC, Athens
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networks. Alzheimer's disease is associated with early alterations in cholesterol metabolism, lipid droplet accumulation, mitochondrial dysfunction, and defective autophagy, particularly in APOE4 carriers
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framework, covering a wide spectrum from RANS approaches to high-fidelity LES with automatic mesh adaptation. In parallel, recent work has led to the development of multi-fidelity modeling strategies
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