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application of state-of-the-art imaging techniques to study perturbations in replication fork dynamics genome-wide at single-molecule resolution. They will also have the opportunity to work closely within a
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coordinated in space and time is still unclear. We have developed new tools to address these questions, and we are determining how stable microtubule attachment is restricted to a single locus on each human
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microscopy, Seahorse assays, handling radiolabeled molecules, and single-cell RNA sequencing. A successful candidate will be expected to draft high-impact papers, be highly collaborative, and be comfortable
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. The research focuses on understanding how the immune system recognizes donor HLA molecules by analyzing rare antigen-specific B cells, their function, genetics, and role in transplant rejection. The lab has
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Nanopore, with a strong emphasis on single-molecule chromatin fiber profiling (e.g. Fiber-seq). Applies and/or develops epigenomic and transcriptomic assays such as CUT&RUN and RNA-seq (including specialized
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Polymerase Allocation Under Stress How does a single bacterial cell decide which genes to switch on when it is under attack? When bacteria face stress, such as during infection or antibiotic exposure
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. JOB DESCRIPTION AND POSITION REQUIREMENTS: Postdoctoral Position working on single molecule imaging and gene regulation One Postdoctoral Position is available in the lab of Dr. Manyu Du
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single molecule optical tweezers-fluorescence microscopy. Researchers with training/expertise in expressing and purifying recombinant proteins from the baculovirus/insect cell expression system are highly
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molecules in chemistry, pharmaceuticals, and agrochemicals. The position provides a unique opportunity to work at the forefront of computational chemistry and AI, contributing to high-impact research with
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in the area of single-molecule biophysics of the nucleosome, RNA polymerase II, and chromatin remodelers. The position requires a Ph.D. in an area of physical or biological sciences or equivalent