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or early intervention. To this end, we integrate genetic studies with gene expression and epigenetic marks (e.g., DNA methylation, chromatin accessibility) in cells that are relevant to asthma and allergy
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 1 hour ago
psychosocial stress with neuropsychiatric disorders. The successful candidate will work in an interdisciplinary environment and will lead epigenome-wide analyses in DNA derived from both large-scale studies in
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relationship between DNA methylation variants and gene expression. In a collaborative project between the Netherlands Institute of Ecology (NIOO-KNAW) and Utrecht University (UU), we will tackle these challenges
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: alignment, quantification, differential expression, and functional analysis Useful tools: STAR, HTSeq, DESeq2, clusterProfiler Tumor DNA sequencing analysis: alignment, somatic variant calling, and functional
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-wide DNA methylation and histone modification profiles will be examined to assess epigenetic integrity. Among the key duties of this position are the following: Maintain and manage mouse colonies
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may contribute to projects involving: multi-omics analyses (single-cell, cell-free RNA/DNA, methylation, proteomics); biomarker discovery for pregnancy complications and neonatal outcomes; computational
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. Main research lines Study of the “language” of chemical modifications in DNA and histones (epigenetics) and RNA (epitranscriptomics). Characterisation of multi-omic heterogeneity through single-cell
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to projects involving: multi-omics analyses (single-cell, cell-free RNA/DNA, methylation, proteomics); biomarker discovery for pregnancy complications and neonatal outcomes; computational biology, machine
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. The employee will perform all aspects of DNA isolation, mutation detection in human disease associated genes, real-time Q-PCR analysis for gene dosage and mosaicism analysis, NGS library preparation, sequence
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(alternative splicing and DNA methylation) to refine the prognostic stratification of IDH-wildtype Glioblastoma. The activity includes: 1) In silico bioinformatics analysis on public datasets and data