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combining high-plex imaging, spatial data analysis, and machine learning. One arm of the project will seek to engineer diverse quantitative features (e.g., adapting concepts and metrics from network science
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outside the liver. There is an unmet need to develop novel therapeutic strategies that can impact on survival of BTC patients. Here we will test novel compounds in multicellular, patients’ derived
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Project description: The TPL-2 kinase is a key activation of mitogen activated protein kinases (MAPK) in innate immune cells and is required for the inducible production of inflammatory cytokines during
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