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are particularly encouraged. Areas of interest may include, but are not limited to: • Mechanisms of DNA damage recognition and repair • Genome stability and chromosomal rearrangements • DNA replication and
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sequencing library preparation, mammalian cell culture, lentivirus production, chromosome conformation capture techniques (e.g. 3C, Hi-C), chromatin immunoprecipitation, ATAC-Seq, FACS, flow cytometry
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, some strains of mice can taste certain bitter or sweet tastants while others can't. Based on these variations, the bitter and sweet taste loci have been mapped on human or mouse chromosomes. By using
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chromosome. Hinshaw, S., Quan, Y., Cai, J., Zhou, A., & Zhou, H. (2023). Multi-site phosphorylation of yeast Mif2/CENP-C promotes inner kinetochore assembly. Current Biology. https://doi.org/10.1016/j.cub
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lab at Harvard Medical School in Boston, Massachusetts. The work of the Colaiacovo lab is focused on investigating mechanisms promoting accurate meiotic chromosome segregation in C. elegans. We welcome
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chromosomal copy-number alterations with protein-defined cell states in intact tissue, linking early genomic changes (e.g., MYC, CCNE1 gains) to local immune microenvironments at single-cell resolution
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a focus on understanding cell division, genome stability, chromosome dynamics, mitochondrial function, and the molecular mechanisms underlying human health and disease. Cohesin, cellular adaptation
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cytogenetic, cytogenomic, and molecular genetic testing, including chromosome analysis, FISH, copy number analysis, genomic microarray, sequencing, and other genomic assays for both oncology and constitutional
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includes but is not limited to chromosome analysis, chromosomal microarray and Fluorescent In-Situ Hybridization (FISH). Position includes opportunity for advancement to Technologist I and further. Hands
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experiments. Aim 2. To uncover how genome scrambling and chromosomal breakpoints generate gene-loss alleles, and to assess their potential adaptive impact to ocean environmental conditions. THE TECHNIQUES