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/science.aea5113) Stockis J et al. Science Immunology 2024 (DOI: 10.1126/sciimmunol.adl1903) Schuijs MJ et al. Nature Immunology 2020 (https://doi.org/10.1038/s41590-020-0745-y ) Preferred skills/knowledge Cell
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of the “Cell Signaling and Pathogenesis” team: https://cimiparis.fr/equipes/robert-weil/ Where to apply E-mail [email protected] Requirements Research FieldBiological sciences » BiologyEducation
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-relevant models that link molecular and cellular findings to disease mechanisms and clinical relevance. The work includes advanced cell culture of various cardiovascular cell types, 3D cell models, spheroids
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human endothelial cell culture and perturbation systems with genomic discovery tools to dissect how genetic variation at CAD-associated loci operates through the vessel wall. Active research areas include
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techniques in cell culture (routine cell maintenance, transient transfections, preparation of nuclear extracts, utilization of CRISPR/Cas9) Assist with fluorescent imaging techniques, both biochemical and in
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at https://biffilab.wordpress.com Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. A major recent advance has been the development of KRAS inhibitors, which have shown
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stress affects specific cell types in the nervous system and the gut, using human pluripotent stem cell (hPSC)-derived models of the enteric nervous system. Our work sits at the intersection of stem cell
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project management. Ability to work independently while contributing effectively within a collaborative research team. Ability to learn quickly & multitask. Knowledge and skill in cell culture, molecular
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following techniques: mammalian cell culture, bacterial culture and growth assays, fluorescence and confocal microscopy, molecular cloning, genetic manipulation of mammalian cells and bacteria, quantitative
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mouse models, in vivo rabbit preparations, and cell culture approaches to study how anesthetics induce unconsciousness and cause toxicity. Our wet bench experiments involve measuring oxygen consumption in