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addition to this unique and powerful animal model, we employ a broad range of approaches, including human pluripotent stem cells, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial
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, or interoception. Adipose tissue biology, thermogenesis, metabolic physiology, glucose and lipid metabolism, obesity and diabetes models, or mouse metabolic phenotyping. Single-cell genomics, spatial transcriptomics
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to be educated and enlightened citizens who lead productive and meaningful lives. Vision To be the national model for the engaged university: engaged with ideas and the world. Who We Are Situated in
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) investigates the chemistry and transport of trace substances in the troposphere. To this end, field and simulation chamber experiments as well as model simulations are conducted. Our research in the “Atmospheric
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from aquatic sediments represent a major uncertainty in the global carbon cycle. This project seeks to advance our mechanistic understanding of methane gas dynamics across multiple spatial scales by
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Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento _IST-ID | Portugal | 2 months ago
refinement Identify missing physics from simulations (spatial inhomogeneity, back-reaction, attractors) and propose model extensions or semi-empirical corrections. Derive/implement models and fit parameters
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Memorial Sloan-Kettering Cancer Center | New York City, New York | United States | about 2 months ago
from blood and tissue samples of cancer patients treated with immunotherapy. These data include flow cytometry, scRNA-seq, spatial transcriptomics, and co-registered multiplex immunofluorescence (mIF
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genetics, genome engineering, advanced microscopy, quantitative image analysis, single-cell and spatial multi-omics, biomaterials, and engineered in vitro model systems to investigate how the aging
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team. Perform spatial integration (alignment, upscaling/downscaling) for comparative analyses. Assess the distribution of modeled exposures and health impacts across population subgroups. Contribute
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German Cancer Research Center in the Helmholtz Association (DKFZ) | Oettingen in Bayern, Bayern | Germany | about 2 months ago
studies with patient-derived models and clinically relevant preclinical systems, we seek to identify novel therapeutic vulnerabilities that can ultimately improve treatment options for patients with SCLC