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Field
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alterations impact human lymphocyte development. By combining CRISPR-based genome engineering, induced pluripotent stem cells (iPSCs), and advanced thymus and bone marrow organoid systems, we study both
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– signaling – proteasome – ubiquitination – multiple myeloma – mantle cell lymphoma – cancer – immunology – inflammation – infection – streptococcus – CRISPR/Cas9 – proteomics – targeted therapy Website
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. The project will use quantitative mitochondrial-tracing approaches, including a recently established HiBiT-based platform, live-cell imaging, CRISPR-engineered cancer models and tumour–stromal co-culture
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-domain proteins. Research program The project will establish a targeted CRISPR-based functional screening strategy for LCCL-domain proteins in Cryptosporidium. The postdoctoral researcher will
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ambitious research project that bridges translational and clinical science? In our lab, your work directly contributes to science that makes a difference. The Salzer Group combines CRISPR engineering of
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mammalian cell culture, plasmid-based molecular biology, gene manipulation/CRISPR-Cas9, protein and matrix assays, and development of in vitro models. The position will work across Penn and CMCVAMC and is
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involvement across the 3 work packages (snRNAseq, vascular organoids, CRISPR validation). Chronic kidney disease (CKD) affects around 10% of the world's population and drives major vascular remodeling
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foundational support for a human genetic and immunological theory of severe infectious diseases. For more information, visit https://www.hgid.org/ About the Role We are seeking a motivated, adaptable, and team
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at https://biffilab.wordpress.com Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. A major recent advance has been the development of KRAS inhibitors, which have shown
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genetics, gene therapy, CRISPR-based gene editing, stem cell technologies, and translational disease modelling. We are particularly interested in developing treatments for retinal disorders prevalent in