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at the University of Nottingham in collaboration with Erebagen Ltd to screen engineered bacterial natural product libraries for anti-cancer activity using native mass spectrometry. This exciting project is supervised
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. They should have expertise in HPLC, the interpretation of NMR and Mass spectrometry data as well as significant experience in synthetic organic chemistry. Practical experience in enzyme assays would also be
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are: Does fertilizer placement play a key role in crop establishment? Native mass spectrometry for the discovery of new anticancer agents Requirements Applications are invited from students with backgrounds
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involving exercise and implementation of stable isotope tracers. The study will involve collection of biological samples and subsequent analysis using mass spectrometry and molecular biology techniques
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for testing the enzymatic activity will be developed over the course of the PhD and the enzymes will be characterised via a variety of analytical methods (e.g. biochemical assays, mass-spectrometry
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-culture model development, mass spectrometry, matrix biology, structural analysis, and a good understanding of glycobiology. You will work within a highly skilled, collaborative, and exciting research team
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sample drying, milling, digestion, dilution, prior to undertaking routine analysis by inductively coupled-plasma mass spectrometry (ICP-MS). Sample handling to comply with relevant health and safety and
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methods for testing the enzymatic activity will be developed over the course of the PhD and the enzymes will be characterised via a variety of analytical methods (e.g. biochemical assays, mass-spectrometry