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, in this PhD project we will extend the toolbox of NNZYMES as novel biocatalysts to access various N-N bond-containing compounds. In the laboratory, we thereby combine bioinformatic analysis with enzyme
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knowledge gap, in this PhD project we will extend the toolbox of NNZYMES as novel biocatalysts to access various N-N bond-containing compounds. In the laboratory, we thereby combine bioinformatic analysis
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compounds. In the laboratory, we thereby combine bioinformatic analysis with enzyme biochemistry, organic chemistry, instrumental analysis, and protein engineering to elucidate diverse N-N bond-forming
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We are looking for two highly motivated and enthusiastic PhD candidates with a strong background in microbiology, bioengineering, bioinformatics or closely related fields to join the Systems Biology
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in microbiology, bioengineering, bioinformatics or closely related fields to join the Systems Biology of Predatory Bacteria group of Dr Renske van Raaphorst. The bacterial predator Bdellovibrio
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: 33398343]; Incarnato et al., 2017 [PMID: 28934475]; Incarnato et al., 2017 [PMID: 28180324]; Incarnato et al., 2014 [PMID: 25323333]) and bioinformatics analysis tools (Morandi et al., 2022 [PMID: 35361788
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, or C-N bond-forming reactions. In the last part of the project, you will make use of third-generation sequencing techniques and bioinformatics tools to map the sequence-structure-function relationships
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., 2014 [PMID: 25323333]) and bioinformatics analysis tools (Morandi et al., 2022 [PMID: 35361788]; Morandi et al., 2021 [PMID: 33619392]; Incarnato et al., 2018 [PMID: 29893890]; Incarnato et al., 2016
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techniques and bioinformatics tools to map the sequence-structure-function relationships of these biocatalysts. Organisation The University of Groningen is a research university, currently in or around the top