-
laboratory skills in molecular biology or biochemistry. A background in genomics and epigenetics or expertise with relevant sequencing methods such as RNA-seq, ChIP-seq, CUT&Tag are desirable. In particular
-
The Sawarkar lab at the MRC Toxicology Unit is looking to appoint a Research Associate (Postdoctoral Fellow) to contribute to its programme on Epigenetics, tRNA transcription and Neurodegeneration
-
the HUSH epigenetic transcriptional silencing complex, which silences newly integrated retroelements (retroviruses/retrotransposons). We recently showed how HUSH distinguishes 'self' from 'non-self' genomic
-
of mouse embryonic stem cells, focusing on uncovering epigenetic and co-factor-dependent mechanisms underlying these processes, including exploring data already collected. There is also an opportunity
-
, JACI 2021 (PMID: 32717253); Progatzky, Jha et al, JACI 2019 (PMID: 31002833); Jha et al, ERJ, 2019 (PMID: 31391224). The project will seek to characterise cellular responses and epigenetic changes
-
analyses of circulating tumour DNA (ctDNA) in liquid biopsies. We leverage epigenetic changes that are specific features of early stage cancers. These studies generate large amounts of genome sequencing data
-
of these cells including proteomic, transcriptomic and epigenetic approaches. We utilise cells isolated from primary human tissue samples and organoid systems. As part of our team, you will contribute to ground
-
studies the mechanisms of epigenetic regulation of developmental processes and genome function in mammals. The current focus of the research group is the role of genomic imprinting in the regulation
-
We seek to appoint a postdoctoral scientist to advance the application of DNA secondary structure and epigenetic features in the early detection of cancer. This post is funded by a new award from