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Apply and key information Summary The study of beta-cell function is limited by supply of viable human islets. Initial studies of insulin secretion involved microdissection of collagenase isolated
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Apply and key information Summary All forms of diabetes are linked to loss of beta-cell mass and function. This was traditionally attributed to alterations of beta-cell proliferation and apoptosis
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cell types that secrete insulin, glucagon and somatostatin plus an increasing number of unsuspected brain-gut peptides. However, intra-islet autocrine or paracrine effects, whereby the secretory products
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synthetic and nutrient derived metabolites may form basis for novel stage-specific treatment targets of melanoma. The work will involve the application of molecular, cell biology and pre-clincial models
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more than one year (or part-time equivalent) are NOT eligible to apply for an award. Please note: you will automatically be entered into the competition for the Full Award, unless you state otherwise in your
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on the system will be deemed your first-choice preference and further applications will be ordered based on the sequential time of submission. If you are successfully shortlisted, you will be
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., Li, Q., Sun, L., Wang, J., & Wei, L., 2022, In: Chem. Rev. 122, p 10087-10125. Metal—organic frameworks in fuel cell technologies; Ren, Y., Chia, G. H. & Gao, Z., 2013, In: Nano Today 8, p 577-597
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the absence of stimulus but convert to their cytotoxic form upon activation. Specific objectives/Methodology: (1) To synthesise and characterise the compounds using standard organic chemistry procedures. (2
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and leads to amputation – 8000 chronic wound patients undergo amputations each year, costing the NHS >£3bn annually.Additional information on the mechanisms controlling biofilm development, and a means
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Applications for more than one PhD studentship are welcome, however if you apply for more than one PhD project within Biomedical Sciences, your first application on the system will be deemed your first-choice