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at the Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden, to study molecular mechanisms that protect against disease-related chromosomal aberrations. The Department of Cell and
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. The disease-associated lncRNAs are investigated in human adipocyte cell models and using CRISPRi/a gene perturbation coupled to lipidomic/metabolomics, we aim to understand the effect of the lncRNA expression
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learning models of the molecular networks within cells. The models encompass metabolism, signaling, and gene regulation and are constrained to align with physical interactions between biomolecules. We train
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human health? Novel molecular imaging technology with PET enables us to detect and map pathological changes in the brain in Alzheimer´s disease and other dementia diseases long before symptoms of memory
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tracing. Your mission is to create a cell model to dissect how specific adipocyte progenitor populations contribute to the generation of different fat cell subtypes. You will work in an interdisciplinary
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a Research Infrastructure? No Offer Description Do you want to contribute to improving human health? Our lab is advancing precision cancer medicine through deep learning models of the molecular
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keen interest in leukemia microenvironment. Experience in working with tumor microenvironment, molecular and cellular biology techniques, multi-color flow cytometry, confocal imaging and mouse modeling
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they are formed. To achieve this, we will employ several state-of-the-art approaches including lineage tracing in transplantation models and advanced cell biology work based on human cells. Your profile To be
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. Proteins and glycans of interest will be enriched by affinity purification from human brain tissue, blood samples and cerebrospinal fluid as well as from mouse models and neuronal cultures. Liquid