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macrophages toward a pro-inflammatory, anti-leukemic state. The work will combine human monocyte-derived macrophage models, leukemia-conditioned macrophages, primary AML patient samples, chemical biology
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cells. Compounds identified through a pharmacological screening approach represent promising therapeutic leads, including in models of bortezomib-resistant cell lines. The project combines a fundamental
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. This large multimodal dataset allows us to estimate and test different computational models of the decision and learning processes. One postdoc is currently working on the MEG and iEEG data, and one PhD
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psychometric modelling as well as with fMRI in a large pediatric cohort, with the aim of building one of the largest open datasets on brain development for mathematics. Role The successful candidate will be
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between cellular approaches, experimental models and translational issues, and strengthens PIMIT's position in the study of infectious mechanisms in contexts of recurrent exposure. It contributes
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integration of theoretical and experimental approaches to redefine biological questions, develop innovative experimental strategies, and enhance data analysis and modeling of complex biological systems. It aims
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develop and lead independently a research project applied to the two main pathophysiological models of CD5+ chronic B cell neoplasms (chronic lymphocytic leukemia and mantle cell lymphoma) of the host
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Nantes, Nantes-Saint-Nazaire School of Fine Arts, Nantes School of Architecture (ENSA Nantes). Nantes University proposes a sustainable and open university model that aims to build a more fair and
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modelling and mechanistic exploration of heart–brain circuits. Summary of the teaching project: The teaching project aims to structure coherent educational activities centered around animal physiology, with a
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, tumorigenesis, and therapeutic resistance. This project aims to develop microscopy techniques capable of high-dimensional and temporal phenotyping, applicable to 2D/3D models and clinical samples, to characterize