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cells. Compounds identified through a pharmacological screening approach represent promising therapeutic leads, including in models of bortezomib-resistant cell lines. The project combines a fundamental
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. The Institute aims at strengthening the continuum of health research from fundamental molecular studies to clinical applications, while fostering pioneer research approaches. The “Chaire INSERM” project
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details in https://umr-right.com ). Summary of the scientific project: The maintenance of T cell effector functions in vivo are critical for the success of cancer immunotherapies including Immune checkpoint
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Nantes, Nantes-Saint-Nazaire School of Fine Arts, Nantes School of Architecture (ENSA Nantes). Nantes University proposes a sustainable and open university model that aims to build a more fair and
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at deciphering fundamental principles underlying biological structures and processes by integrating experimental data with computational models to uncover insights into genome evolution, molecular mechanisms, and
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), functional (neuroendocrine and neuroimmune axes), and molecular pathways. This interconnection plays a central role in regulating metabolism, cardiac function, stress responses, and cognitive and emotional
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and innovation. Strategy of the host laboratory: The objective of the CRCT (U1037) is to attract and retain talented scientists who will become tomorrow’s leaders at the interface of molecular biology
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response to vaccination. The approaches developed will combine molecular biology, omics analyses, and bioinformatics, using both experimental models and clinical samples. This chair fully aligns with