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, integrating statistical inference, machine learning, and population genetics. We will develop advanced computational methods to characterize the functioning of T- and B-cell repertoires. The goal is to build
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on the development of novel solid-state nuclear magnetic resonance (NMR) methodologies to investigate the molecular organization and remodeling of the fungal cell wall. The successful candidate will be appointed for a
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engineers (technical staff) will assist the PostDoc for all what concerns hardware/software development and maintenance of the robotic platforms. Where to apply Website https://emploi.cnrs.fr/Offres/CDD
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motifs; - establish, optimize, and apply quantitative protein-interaction assays; - perform mammalian cell culture, molecular cloning, mutational analysis, recombinant protein work, and fluorescence
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between PLA2R1 and patient antibodies, both in vitro and in vivo. Develop inhibitors of these interactions and validate them in various assays. Present results, interpret data, validate findings, and take
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in the growth of melanoma cell xenografts in isogenic mice; to determine how GATA6 modulates the tumor immune microenvironment (immunohistochemical staining of tumor sections, transcriptomic analyses
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and the RespirERA University Hospital Institute (IHU RespirERA). Mapping Molecular Cell States of Susceptibility to Immune Effectors in Lung Cancer Where to apply Website https://emploi.cnrs.fr/Offres
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, proficiency in English is essential. Membrane Traffic and Morphogenesis: Quantification of Membrane Flows in Embryonic Tissue Development Tissue morphogenesis results from the complex interaction of mechanical
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Drosophila and/or mouse models. • Prepare and analyze samples for single-cell and/or single-nucleus sequencing approaches. • Participate in the development and use of 3D spatial transcriptomics approaches
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neural stem cell (NSC) niche. Recent studies have revealed key aspects of human rhombic lip (hRL) organization and shown that defects in its development underlie several human syndromes. These findings