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human iPSC derived retinal GACR models and perform tailored therapeutic screens with repurposed medicine taken from the parallel SYMPATHIC consortium (Karnebeek and coworkers 2023). The candidate will
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of type 2 diabetes In this project, we will study disrupted communication between fat tissue, capillaries and muscle cells as an early cause of type 2 diabetes. We will create human muscles in a dish from
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applicants for a PhD position in Stem cells and Multiple Sclerosis (MS). Your work will focus on human iPSC-based models of inflammation and MS to study microglial cell functioning in a white matter- and grey
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your findings in an array of cellular iPSC-models present in the lab, compare these to known iPSC- and human patient datasets and define a mechanism of action. You will then work with an (inter)national
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to disease models; Align these findings with human disease. Requirements Specific Requirements You have a master's degree in a field related to biomedical sciences, (medical) biology, biochemistry
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barriers”. Therefore, their strict neurotoxicity assessment is essential to determine safety for human exposure. Such hazard assessment requires human in vitro models which closely represent functional human
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, 2024). We are seeking an enthusiastic candidate for one of the projects that is funded by ZonMW: Prof P.L. Hordijk - Innovative modelling of the human microcirculation by merging vascular cell biology
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these findings with human disease. Requirements Specific Requirements You have a master's degree in a field related to biomedical sciences, (medical) biology, biochemistry or bioinformatics; You have experience in
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depressive symptoms, and these more often remain chronic than in younger populations. The relationship between mental health and daily functioning is complicated: functional decline is one of the causes
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this collaborative project, we will investigate the mechanisms of tRNA gene regulation using novel methods and technologies in human cells and budding yeast. We will take advantage of CRISPR-mediated approaches, high