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-wide DNA methylation and histone modification profiles will be examined to assess epigenetic integrity. Among the key duties of this position are the following: Maintain and manage mouse colonies
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(alternative splicing and DNA methylation) to refine the prognostic stratification of IDH-wildtype Glioblastoma. The activity includes: 1) In silico bioinformatics analysis on public datasets and data
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, or computational analysis of clinically annotated cancer datasets. Experience with multi-omics data integration, including DNA sequencing, bulk and single-cell RNA sequencing, spatial transcriptomics, methylation
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with experimental and clinical teams. Primary Responsibilities * Lead computational analysis of large-scale multi-omics datasets, including transcriptomic, epigenomic (DNA methylation, chromatin
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. To do so, the researcher will notably analyze bulk and single-cell multi-omics datasets (gene expression, DNA methylation, chromatin accessibility, transcription factor binding, and others) from mouse and
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, and the NCI, and has extensive collaborations with the McDonnell Genome Institute. Position will play a lead role in new studies of epigenetics, DNA methylation, and gene regulation in acute myeloid
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investigating the functional and regulatory dynamics of ghost introgression, combining whole-genome sequencing, allele-specific expression analyses, and DNA methylation profiling across managed Red Wolves
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Institute of Genetics and Animal Biotechnology of the Polish Academy of Sciences (formerly Institute of Genetics and Animal Biotechnology PAS) | Poland | about 1 month ago
techniques (DNA, RNA, and protein isolation from tissues, PCR, RT-qPCR, ELISA tests); experience in conducting research in the field of epigenetics will be an advantage. 5. Fluency in spoken and written
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, DNA methylation, RNA-seq, proteomics, lipidomics and metabolomics in large-scale human populations. The lab is interested in integrating and mining the different types of data to understand the genomic
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. Essential Duties and Responsibilities Analyze large-scale next-generation sequencing (NGS) datasets, including whole genome/exome sequencing, RNA-seq, and DNA methylation data. Develop and implement state