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work has appeared as first- or co-first-author publications in Nature Cancer, Nature Genetics, and Cell Stem Cell, spanning statistical method development, cancer transcriptional regulation, and spatial
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. Mutations and deletions of NR2F1 lead to Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Using neuronal cells derived from CRISPR/Cas9 engineered human induced pluripotent stem cells (hiPSC) we model
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investigating tertiary lymphoid structures in inflammatory diseases, interorgan endocrine signaling, the comparative niches of stem cells across tissues, or mechanisms of transcriptional regulation such as
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challenges in stem cell research, aging and disease modeling. The group employs methodologies from different areas of mathematics, engineering, and physics, and integrates multiple sources of biological