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Long-term culture-initiating cell (LTC-IC) assays or xenotransplantation-based stem cell assays. - Sequencing & genomics support including Library preparation for next-generation sequencing (targeted
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of standard operating procedures. Conduct hands-on research in reproductive immunology and maternal-fetal immune programming using mammalian cell culture, rodent pregnancy models, infection or immune challenge
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roles for oxidative stress-related signaling steps in the onset of nuclear oxidative stress leading to beta cell death under diabetogenic conditions. Conduct proteomic studies for the identification
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used for biochemical studies including Western blots, RNA-Sequencing, lipid analysis, qRT-PCR, and biochemical assays. Additional projects may include RPE cell cultures and human donor tissues. It is
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Summary The fellow will be involved in studies, which are aimed at understanding G protein-mediated signaling mechanisms underlying islet beta-cell function in health and diabetes. Specifically