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of the proteome in cells with structural proteomics approaches. Our research program focuses on pathogenic members of the family Vibrionaceae with a strong emphasis on the intestinal pathogen Vibrio cholerae and
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infected human cells, identify viral and host complexes in their native context, and combine this with structural modeling and proteomics to build a spatially and temporally resolved picture of the infection
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, brain organoids, genome editing, high-resolution imaging, single-cell sequencing, spatial transcriptomics, epigenomics, and proteomics, as well as a unique mouse model in which neural progenitors acquire
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, single-cell transcriptomics, proteomics, metabolomics, and network reconstruction. Former trainees of the Chi lab have been principal investigators in multiple academic institutions. Please also see the
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outcomes among survivors of European and African ancestries; 2) analyses of multi-omics (genomics, transcriptomics, proteomics, and metabolomics) and system genetics (e.g., eQTLs regulating molecular
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, single-cell transcriptomics, proteomics, metabolomics, and network reconstruction. Former trainees of the Chi lab have been principal investigators in multiple academic institutions. Please also see the
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. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, metabolomics, RNAseq, transgenic/knock-out technology, and animal facilities from