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The Yang Lab in Department of Surgery at St. Jude Children's Research Hospital is seeking a highly motivated Postdoctoral Fellow to join our translational research team. The research focuses
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. • Direct experience with isolation and functional characterization of GPCRs and their signaling partners (G-proteins, arrestins, GPCR kinases, etc.) is strongly preferred. Selected Publications: Parallel
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by cryo-electron tomography, including cell culture under BSL-2 containment, vitrification, cryo-FIB milling and tilt-series collection Process tomograms and characterise macromolecular complexes by
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al, Nature Cancer , 2026). Research Focus & Responsibilities Process clinical samples for next-generation sequencing and multi-omic profiling Contribute to studies involving liquid biopsies and single
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metabolic processes that control stem cell development, blood disorders, and childhood cancers. We employ high-throughput metabolomics, epigenomics, single-cell multiomics, (epi)genome editing, and
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are often tied to their subcellular localization and the biological processes they are involved in. We have extensively characterized how the molecular grammar of prion-like low-complexity domains encode
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lab studies how normal development processes are perturbed to drive pediatric embryonal tumors using rhabdomyosarcoma as a model system. Our findings defined the cell of origin of rhabdomyosarcoma, a