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health. Basic science discoveries made using a variety of human and pathogen-derived proteins, designed, expressed and purified by a collaborative DHVI team have contributed to the identification
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cryo-EM workflow, including sample preparation/freezing, data collection, processing, and atomic model building. Biochemical/Biophysical Characterization: Managing protein engineering (cloning
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performed on-site or at a designated assignment location. Be Bold. Responsibilities include protein expression and purification, enzymatic and spectroscopic analyses, molecular biology, natural product
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chain and resource data sets. The Postdoctoral Associate will be based in Duke’s Department of Civil and Environmental Engineering and the research team led by Professor Heileen Hsu-Kim. The Postdoctoral
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of cancer, and/or biochemistry. Prior experience in stem cells, vascular biology, 3Dorganoid cultures or protein interactions is advantageous. Evidence of successful completion of a research project
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proteins and their complexes with host receptors and antibodies, biophysical and biochemical analyses to complement structural results, and collaborations with virology and immunology labs to understand
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: Mechanistic studies of how m6A alters RNA:protein interactions across the transcriptome Defining the roles of m6A and RNA-binding proteins in brain development, neural function, and neurological disease
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. Specifically, the Post Doc will be focused on studies of signaling by G protein-coupled receptors, and will be performing a number of luminescence- and bioluminescence resonance energy transfer-based assays
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-edge technologies, including genetically engineered mouse models, patient-derived models, single-cell and spatial genomics, organoid systems, and preclinical therapeutic studies. Learn more about our
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procedures and results. Specifically, the Post Doc will be focused on studies of signaling by G protein-coupled receptors, and will be performing a number of luminescence- and bioluminescence resonance energy