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expressing either these promoter-reporter constructs or glucocorticoid receptor (GR) reporter plasmids will be constructed. Cell lines of interest include placental JEG3, colon SW620, and renal RCCD2
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Determination of the placental transport of MNP and MNP-allergen complexes to estimate fetal exposure Investigation of the immune/inflammatory response of the placenta and fetal immune cells to MNP and MNP
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plasmids will be constructed. Cell lines of interest include placental JEG3, colon SW620, and renal RCCD2 for HSD11B2, and hepatic and macrophage cell lines for HSD11B1. Compounds that will be included in
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(MWRI), which is one of the largest institutes dedicated to reproductive biology and women’s health. Research at the Institute centers on embryonic, fetal, and placental development, pregnancy