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About the Lab A PhD student position on the design and application of fluorescent protein-based biosensors in neurodegenerative disease is immediately available at the Messens Lab. Successful
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PhD Student Position: Design and Application of Fluorescent Protein-Based Biosensors in Neurodegenerative Disease Project Description This exciting opportunity involves research at the intersection
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Topic Amyloidosis disease is the abnormal accumulation of protein in amyloid conformation in vital organs and tissues throughout the body, ultimately resulting in multiorgan dysfunction, organ
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RNA-Seq, ChIP/DAP-Seq protein-DNA interaction data, bulk, and single-cell ATAC-Seq) and the application of diverse supervised machine learning approaches (e.g., feature-based, deep learning, and
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structural characterisation of prostate cancer target proteins for the development of inhibitory compounds. DC8 (UNamur) will identify compounds and peptides active on prostate cancer target proteins, also by
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from membrane permeability calculations, for instance by reducing memory in the simulations. Developing new methods for screening of the binding kinetics of candidate cancer drugs to protein binding
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(RTT) and MECP2 duplication syndrome, both caused by abnormal dosage of MECP2 protein. We have developed a xenotransplantation model for both disorders, as well as novel ways to investigate
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of bioactive peptide-based ligands or small molecules, including the synthesis of custom amino acids when required. You will participate in discussions that guides the design and optimization process of
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, for instance by reducing memory in the simulations. - Developing new methods for screening of the binding kinetics of candidate cancer drugs to protein binding sites, with application in precision medicine
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biomolecules/particles such as viral vectors from biostreams. DC5: The main scope of this PhD lies in the handling of more concentrated streams, for example, protein harvesting via heterogenous membrane