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/science.aea5113) Stockis J et al. Science Immunology 2024 (DOI: 10.1126/sciimmunol.adl1903) Schuijs MJ et al. Nature Immunology 2020 (https://doi.org/10.1038/s41590-020-0745-y ) Preferred skills/knowledge Cell
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at https://biffilab.wordpress.com Pancreatic ductal adenocarcinoma (PDAC) remains a formidable clinical challenge. A major recent advance has been the development of KRAS inhibitors, which have shown
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cell culture and biological assays Additional Information Benefits What can you expect from us? 232 vacation hours per year, based on a 38-hour workweek (1.0 FTE). You can also work more or fewer hours
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their website at https://www.naritalab.com/ Our laboratory investigates the biology of preneoplastic cell states, with particular interest in how changes in cell functional identity and plasticity are controlled
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, functional and metabolic analyses, and co-culture models with tumour microenvironment cells. In vivo experiments using orthotopic mouse models will enable the study of their role in tumour formation and
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. The project will use quantitative mitochondrial-tracing approaches, including a recently established HiBiT-based platform, live-cell imaging, CRISPR-engineered cancer models and tumour–stromal co-culture
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mammalian cell culture, nucleic acid work, or immunofluorescence staining. Hands-on experience of fluorescence microscopy, or of optics and instrument building. Exposure to next-generation sequencing, either
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: An MSc (or equivalent) in biomedical sciences, stem-cell biology, ophthalmic research, neuroscience, bioengineering, or related fields. Experience (or strong interest) in cell culture, molecular biology
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microphysiological systems, perfusion platforms, and advanced human in vitro models Cell culture and functional characterisation of bioprinted constructs Your profile Master’s degree (or equivalent) in biomedical
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biology, molecular biology and animal models to investigate how these hybrid cells favour carcinogenesis. Where to apply Website https://app.smartsheet.au/b/form/019eedeef91978fdbc2b67718479eac6?project_id