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this project, we will dissect functions of C-degron pathways through a combination of high-throughput screening, molecular biology, genetics and biochemistry. We will take advantage of powerful yeast genetics
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vitro for both yeast and mammalian system using bulk biochemistry and single-molecule imaging (SMI) techniques, supported by cell biology. This PhD project will involve characterizing the molecular
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are looking for a PhD student with a strong interest in mechanisms of gene regulation, genomics, evolutionary biology and/or biochemistry. Our ideal candidate would like to combine wet lab and computational
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strong background in cell biology (molecular biology, biochemistry or related). A high motivation for fundamental biology and excellent teamworking skills are required. If you are interested in
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genetics, molecular and cell biology with protein biochemistry and advanced genomics tools, using both budding yeast and human cells as models. PhD Project 1: Deciphering the ubiquitin code The ubiquitin
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approaches. We encourage applications of highly motivated PhD candidates with a strong interest in structural biology, protein biochemistry, biophysics and structure-function relationship and a significant