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Hematopoietic stem cells (HSCs) ensure the lifelong production of all blood cell types. With age, HSCs undergo functional and molecular changes that impair their regenerative capacity and contribute
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, neurodegeneration, advanced microscopy, stem cell biology, and cell biology. The project will leverage state-of-the-art imaging facilities and established human iPSC-derived models of Alzheimer's disease. The work is
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-induced wounds. At the molecular level, frequent exposure to acute or chronic tissue damage in epithelial tissues has recently been shown to activate plasticity mechanisms, with a deep impact on the cells
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cells. Proteomic approaches have identified several surface proteins that are overexpressed in glioblastoma stem cells compared with non-tumour cells, and whose role in glioblastoma biology remains to be
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neural stem cell (NSC) niche. Recent studies have revealed key aspects of human rhombic lip (hRL) organization and shown that defects in its development underlie several human syndromes. These findings
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cells including macrophages). - Modelling of CKD-like vascular injury in 3D vascular organoids derived from induced pluripotent stem cells (iPSCs), exposed to phosphate, uremic toxins and pro-inflammatory
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at the IBDM (Institute of Developmental Biology of Marseille) within the “Physical approaches to cell dynamics and tissue morphogenesis (PoM)” team, and at IUSTI (University Institute of Industrial Thermal
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“Signalling and Cytoskeleton Dynamics” research team at the Cell Biology Research Centre of Montpellier (CRBM). A thesis monitoring committee will be established to oversee the progress of the research through
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of Clermont-Ferrand. This joint research unit (UMR) currently comprises 43 permanent researchers and a total of 102 staff members, including contract staff, PhD students and postdoctoral researchers. The LAPSCO
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of representation and neural correlates in human infants and adults (fMRI, EEG and/or fNIRS methodologies). We are looking for a highly motivated candidate with: a Master's degree (or equivalent) in Cognitive Science