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extracellular vesicles. The delivery of RNA into the cytosol represents a major challenge for the development of new delivery strategies and RNA-based therapies. Indeed, following cellular internalization, RNA
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in vitro model. The recruited PhD student will contribute to the three research axes of the project: - Single-nuclei RNA sequencing (snRNAseq) of microdissected arterioles from children with normal
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libraries will be generated: one for 3′ SN RNA sequencing and one for SN ATAC-seq. Sequencing will be performed using short-read, paired-end sequencing, with sufficient depth to detect approximately 3,500
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