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active molecule in Fabry disease and in the production of the glycosphingolipid Gb3. The project will focus on optimizing the molecular structures in order to improve their pharmacological properties and
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with multiple electrodes – multipolar catheters – are increasingly used to facilitate electroanatomic mapping of the atria before ablation. Despite advances in ablation technology, the search for optimal
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. This thesis aims to model, optimize, and experimentally validate such an optical ultrasound sensor based on resonant metasurfaces. The work will focus on three main areas: 1. Multi-physics Modeling: Development
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of the tissue using water-soluble clearing and refractive index matching media, and evaluating the benefits of this approach for three-dimensional imaging. The first year of the project will focus on optimizing
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perfusion and mechanical stimulation in tumor tissues to investigate their poromechanical properties and optimize molecular transport within explants. The successful candidate will be involved in: - Designing
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crack initiation and propagation; Development and validation of a digital twin with an appropriate level of maturity; Proposal and evaluation of new cluster architectures; Validation of optimized
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capable of predicting optimal PISA formulations and significantly reducing experimental screening efforts. The successful candidate will receive multidisciplinary training spanning polymer chemistry
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(bbγγ) channels. In the classical HH(bbγγ) analysis, the H(γγ) channel is treated as a major background process for the di-Higgs channel. A joint analysis of both modes would optimize the overall