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an antiviral testing pipeline without the need for animals models. This doctoral project will focus on developing patient-derived organotypic models to test and optimise broad-spectrum antiviral therapies
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bed play an important role. Reduced blood flow, leakage of the blood-brain barrier and the accumulation of harmful proteins often occur together. In this project, we test the hypothesis that leakage
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white matter. The network aims to strengthen the full translational pathway, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and
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white matter. The network aims to strengthen the full translational pathway, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and
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the brain white matter. The network aims to strengthen the full translational pathway from disease mechanism and model development to preclinical therapy testing, clinical readiness and patient-informed
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white matter. The network aims to strengthen the full translational pathway, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and
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accumulation of harmful proteins often occur together. In this project, we test the hypothesis that leakage of the blood-brain barrier disrupts the glymphatic system. This may accelerate the aggregation
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mechanisms and developing disease models to preclinical therapy testing, clinical readiness and patient-informed treatment priorities. To achieve this, POLARIS brings together expertise in leukodystrophy
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white matter. The network aims to strengthen the full translational pathway from disease mechanisms and model development to preclinical therapy testing, clinical readiness and patient-informed treatment
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the brain white matter. The network aims to strengthen the full translational pathway from disease mechanism and model development to preclinical therapy testing, clinical readiness and patient-informed