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communication pathways in cell biology - the “self-eating” process of autophagy. Autophagy protects us from infections, cancer and neurodegerative diseases and has been shown to promote longevity in model
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Autophagy is an evolutionarily conserved self-eating process mainly purposed to eliminate or recycle dysfunctional cellular organelles or unused proteins. Autophagy plays an important role in development and
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investigation to elucidate the mechanism of autophagy in regulating cancer metabolism and immune response for KRAS-driven lung tumorigenesis and therefore to provide potential treatment for KRAS-mutant lung under
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specifically, it will address the basic mechanochemical processes that regulate one of the most fundamental communication pathways in cell biology - the “self-eating” process of autophagy. Autophagy protects us
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specifically, it will address the basic mechanochemical processes that regulate one of the most fundamental communication pathways in cell biology - the “self-eating” process of autophagy. Autophagy protects us
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investigation to elucidate the mechanism of autophagy in regulating cancer metabolism and immune response for KRAS-driven lung tumorigenesis and therefore to provide potential treatment for KRAS-mutant lung under
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stress granule formation and the role of RNA-binding proteins in regulating autophagy and the integrated stress response to the development of RNA-based therapeutics that target key molecules involved in
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autophagy. Autophagy protects us from infections, cancer and neurodegerative diseases and has been shown to promote longevity in model organisms. The PhD work will involve theoretical modelling, in
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are seeking a self-motivated individual to assist the research on selective autophagy of astrocyte in neurodegenerative diseases and in brain metastasis. This is a temporary appointment for 1-2 years
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of the phagophore, Autophagy, 2021. (https://doi.org/10.1080/15548627.2021.1896157 ) 8. C.T. Tan et al., p62/SQSTM1 in liver diseases: the usual suspect with multifarious identities. FEBS J, 290: 892-912, 2023