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and cell-based assays to identify and validate novel intracellular delivery reagents. We are looking for a highly motivated researcher with a strong background in molecular or cellular biology, protein
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contribute to the creation of knowledge by undertaking a specified range of activities within this specific research project, which aims to characterise the roles of natural killer (NK) cell receptors
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, bioRxiv 2026, doi: 10.64898/2026.07.30.741759) for biological systems. You will lead a computational research project extending DMMSs from population-level to single-cell data, combining neural networks
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in molecular biology, cloning and construct preparation, and experience using heterologous expression systems. Experience with mammalian cell culture and functional receptor or ion-channel assays using
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monolayer and 3D cell culture, analysis of DNA damage repair and the replication stress response by microscopy (of foci and fibers), protein biochemistry (immunoprecipitation and western blotting), drug dose
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single-cell genomics. The project involves curating, harmonising single-cell and multimodal datasets, containerising and running, comparing GRN inference tools as a community resource. The role includes
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aiming to develop innovative next generation battery and fuel cell technologies. A key feature of the Centre’s work is that novel & applied technology innovations will be underpinned by fundamental
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-targeted therapeutics. The project combines in vitro and in vivo tumour and blood vessel modelling, tissue histology, advanced imaging, single cell transcriptomics and bioinformatics approaches
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in molecular biology, cloning and construct preparation, and experience using heterologous expression systems. Experience with mammalian cell culture and functional receptor or ion-channel assays using
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-derived myeloid cells, and relevant T-cell co-cultures. Model the PBC liver microenvironment using bile acids, inflammatory cytokines and patient-derived liver-conditioned media. Lead mitochondrial