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led by Prof Bruce Whitelaw and Dr Tom Burdon at University of Edinburgh (Roslin Institute) and Prof Ramiro Alberio at the University of Nottingham. The team’s expertise in genetic engineering, stem cell
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position is especially suited for candidates with an interest in root development and molecular cell biology. All the technologies required for the project are currently performed in our laboratory
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, to develop an in vitro gametogenesis platform. The primary goal of the project is to develop new understanding of germ cell development and to this aim we will use genomic and epigenetic technologies to study
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to understand how root tips sense and respond to compacted soil environment. The high-level objective of the research is to discover key signals, sensing mechanisms and root cell biophysical responses
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relevant PhD). Closing Date: Tuesday 09 April 2024 Reference: SCI096624 Applications are invited for a Research Associate/Fellow to work on a BBSRC funded project investigating cell fate regulation during
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colleagues at the University of Oxford. This work involves developing and testing small molecules as potential therapeutics in cell-based assays and other approaches for validation of on-target and off-target
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of advanced fuels and IC engine operation. Significant prior experience of low/zero carbon fuels and clean combustion modes in both thermodynamic and optical engines is essential. Candidates must also have a
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organ-on-chip type tissue models with particular interest in barrier tissues (lung and skin) and liver. We are specifically interested in inclusion of immune cells in these tissue models. The work
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development, up to and including gastrulation, using single-cell ATACseq and single-cell RNAseq. The epigenome of primordial germs cells will also be examined for histone modifications following isolation
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of genetic risk factors for lung function impairment, and define the mechanisms and biological pathways underpinning the observed associations. In Nottingham, we will use human primary airway cells combined