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on normal and malignant stem and progenitor cells in the hematopoietic system and decodes the role of metabolites, including micronutrients and neurotransmitters, in the tumor microenvironment and their
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phenotypes, with expert advice from a behavioral neuroscientist. Investigate structure-function relationships using disease-causing missense mutants and a variety of cell-based and biochemical functional
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and metabolism influence cellular networks that govern tissue regeneration, cancer and immunity. We dissect the precise mechanisms of how reciprocal interactions between tissue stem cells; immune cells
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Degradation (TPD) therapeutic strategies to abrogate or rewire cancer cell signaling. We have recently established a new discovery platform to expand the landscape of TPD E3 ligases and targeting modalities