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models, with the help of our Engineered Mouse Model Core Facility. Evaluate transcriptome perturbations using next-gen sequencing analysis, RT-PCR, and qPCR. Characterize mouse neurodevelopmental
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Degradation (TPD) therapeutic strategies to abrogate or rewire cancer cell signaling. We have recently established a new discovery platform to expand the landscape of TPD E3 ligases and targeting modalities
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