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macrophages, and the mechanisms by which viruses perturb mucociliary clearance; the candidate will then harness the organ-on-chip technology to develop a more advanced model of the airway that integrates both
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). The successful candidate will join and collaborate with a vibrant, international team that applies experimental evolution to study mechanisms of fitness gain in the eukaryotic pathogen Leishmania. The candidate
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machine learning assisted cellular event recognition) and modeling to dissect quantitatively the feedback fine tuning cell death. Our pojects are currently focusing on studying the impact of mechanical
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systems in Bacteria suggests a mechanism for the diderm-to-monoderm transition. Nat Microbiol 7, 411–422.
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machinery function using mass spectrometry-based in situ cross-linking (Rey, Anal Chem, 2021), single particle cryo-EM and Cryo-Electron Tomography. Availability of small molecule inhibitors also provide
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mechanisms that could constitute relevant targets for new treatments. We are leading the genetic work package of AIMS-2-TRIALS, the largest European project on autism research. The project is focused on deep