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& Sciences (SCMMS) provides an outstanding multi-disciplinary environment for the pursuit of cutting-edge cardiovascular and metabolic research. We study the fundamental molecular, cellular, and physiological
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the relatively near future. The focus for this specific position will be on the societal impacts of extreme heat events, including those severe enough to overwhelm human physiology. Using the case study of
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pathways and stress responses. The project will involve the use of i) iPSC-derived cardiomyocytes and "engineered heart tissues (EHT)" and ii) experimental in vivo models of cardiac disease. We therefore
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, funded by an internal MRC Impact Acceleration Award, we will use currently-collected patient imaging data to further develop computational pipelines to reconstruct personalised image-based computer models