Postdoctoral Fellow (PhD)

The Department of Ophthalmology at Baylor College of Medicine in seeking a qualified, highly motivated and creative Postdoctoral Associate to join the de Paiva lab.  Dr. Cintia de Paiva’s research focuses on the understanding of the interplay of the aging and cathepsin S and generation of auto receptive t cells on the ocular surface and lacrimal gland. 

• Works closely with the PI and other lab personnel performing complex research and research techniques.
• Designs and conducts experiments in a controlled laboratory setting.
• Performs experiments, collects, analyzes and reports data; designs an immunohistochemistry with proper controls and proper detection colorimetric reactions, (HRP, alkaline phosphatase, streptavidin, etc.).
• Designs and performs flow cytometry with fluorescence minus controls, positive and negative controls in cervical lymph nodes, collagenase-digested lacrimal glands and spleens.
• Designs and performs intracellular staining for interferon-gamma, IL-17 and TNF-a.
• Analyzes data using FlowJo software.
• Designs and performs small surgeries as needed (sympathetic axotomy and others).
• Works with animals, including genotyping, husbandry and inducing dry eye protocol.
• Administers oral gavage, ocular topical eyedrops and subconjunctival injections as needed.
• Designs and performs real-time PCR Tagman Probes.
• Analyzes data using the deltadelta CT method.
• Maintains oversight and ensures that laboratory equipment and supplies are clean and sterile, and maintains the cleanliness of the laboratory, orders laboratories supplies and equipment.  

• Ph.D. in Basic Science, Health Science, or a related field.

• Experience as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate is preferred.  Degree in immunology, molecular biology, microbiology or related field and have published in a peer-reviewed journal(s) is preferred.  
• Prior experience using mouse as a model system is recommended.  
• Previous experience in ophthalmology or immunology is a plus.

• Qualified candidates should submit a one-page cover letter stating reasons for their scientific interest in the lab, career goals, a curriculum vitae including technical skills, and the names and contact information of three references.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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CA; PD