Physiological and Structural Systems, National Science Foundation (NSF)

Updated: over 4 years ago
Deadline: The position may have been removed or expired!

Division of Integrative Organismal Systems

Physiological and Structural Systems

Frequently Asked Questions

IOS has updated the frequently asked questions for the core programs solicitation (NSF 13-506).  They can be found at  August 2, 2013 is the next deadline (by Invitation Only) for full proposals.

Name Email Phone Room
William  E. Zamer (703) 292-8413  685N  
Steve  Ellis (703) 292-8413  685N  
Irwin  Forseth (703) 292-8413  685N  
Gary  Gillis (703) 292-8413  685N  
Michael  Mishkind (703) 292-8413  685N  
Mary Beth  Saffo (703) 292-8413  685N  
Sarah  Wyatt (703) 292-8413  685N  


Apply to 13-506

The Physiological and Structural Systems (PSS) Cluster supports research to advance understanding of integrated physiological and morphological mechanisms in organisms. PSS supports hypothesis- and discovery-based research encompassing a wide range of approaches and including all levels of biological organization (molecules through populations).  The Cluster encourages submission of proposals aimed at identifying fundamental design principles of physiological and structural systems and at understanding why particular patterns of functional morphological and physiological mechanisms have evolved. The Cluster encourages modeling and theoretical approaches to augment experimental approaches.  Multidisciplinary research at the interfaces of biology, physics, chemistry, mathematics, computer science and engineering is encouraged. Normally, the PSS Cluster will not support projects that are primarily focused on environmental toxicology or endocrine disrupting chemicals.

Proposals should be directed to one of the three programs described below:

The Symbiosis, Defense and Self-recognition Program (SDS) supports research on processes mediating both antagonistic and beneficial symbiotic interactions, as well as mechanisms of self/non-self recognition within and between species. The program welcomes proposals on the dynamics of initiation, transmission, maintenance and dissolution of these complex associations, including studies of metabolic interactions, immune defenses (especially involving comparative studies, new systems or novel mechanisms), host-symbiont regulation, and recognition, signaling, communication, and reciprocal responses among interacting species. Integrative approaches and attention to emergent effects of symbiotic interactions are encouraged. All aspects of symbiosis are supported, including commensalism, mutualism, parasitism, host-pathogen interactions, and mechanisms of foreign organelle acquisition.

The Processes, Structures and Integrity Program (PSI) supports research on the physiological and structural features that contribute to life processes in plants, animals, microbes, and other organisms.  Broad thematic areas include, but are not limited to sensing and signaling mechanisms, transport, energetics and metabolism, growth and development, stress adaptation mechanisms, biomaterials, muscle physiology, endocrinology, biomechanics, coordination of reproductive processes, gas exchange, circulation and osmoregulation.  Systems approaches that predict or reveal the nature of coordination among functional processes and/or structural components as a means to further the understanding of organismal integrity are particularly encouraged.

The Organism-Environment Interactions Program (OEI) supports research on the structural and physiological traits of organisms that underlie their capacities to live in various environments. Research on organism responses, including stress responses to abiotic environmental factors and organism interactions with biotic components of their environments over time scales ranging from the short-term to evolutionary is supported. The program seeks proposals framed in explicit environmental or evolutionary contexts and focused on understanding how integrated genetic, biochemical, morphological and physiological processes result in the capacities of organisms to live in their dynamic environments. The OEI Program particularly encourages proposals focused on using physiological traits of organisms to improve predictive models of global change.

Program Directors:

William E. Zamer. Organism-Environment Interactions

Steve Ellis.  Processes, Structures & Integrity

Irwin Forseth.  Organism-Environment Interactions

Gary Gillis.  Processes, Structures & Integrity

Michael Mishkind. Processes, Structures & Integrity; Symbiosis, Defense & Self-recognition

Mary Beth Saffo.  Symbiosis, Defense & Self-recognition

Sarah Wyatt.  Processes, Structures & Integrity


What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)
Map of Recent Awards Made Through This Program

IOS Cluster Descriptions

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