Sort by
Refine Your Search
-
Listed
-
Category
-
Program
-
Employer
-
Field
-
Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein School of Biosciences PhD Research Project Self Funded Dr C Guo Application Deadline: Applications
-
. Macroautophagy, commonly known as autophagy, functions as a lysosomal degradation system responsible for eliminating aberrant cytoplasmic components. Within the autophagy process, SQSTM1/p62 assumes a crucial role
-
autophagy, functions as a lysosomal degradation system responsible for eliminating aberrant cytoplasmic components. Within the autophagy process, SQSTM1/p62 assumes a crucial role by serving as a receptor
-
of autophagy in the clearance of Alzheimer’s-linked tau protein. The post holder will support the principal investigator and research team with various experimental procedures, analysis of results and lab
-
function. The researcher will work on the developing in vitro cell based models to evaluate the impact of oligonucleotide treatment on important cellular functions e.g. autophagy. The successful candidate is
-
of skeletal disease and responses to injury. This is a highly collaborative project integrating expertise in inflammation, autophagy and genetics with collaborators in other schools at the University of Bristol
-
of Oxford. Our research uses primary human chondrocytes and fibroblasts in 2D and 3D cell culture systems to investigate age-related changes in senescence and autophagy in the synovium, which may underpin
-
, King A, Blyth K, Adams PD. Genes and Development 2014 Dec 15; 28(24): 2712-25. p53 status determines the role of autophagy in pancreatic tumour development. Rosenfeldt MT, O'Prey J, Morton JP, Nixon C
-
of immunocytochemistry techniques, live imaging and fluorescent microscopy. Experience of assays to characterise endocytic and/or autophagy pathways. Evidence of collaborations with industry. Proven ability to adapt
-
autophagy mediated by Fis1. EMBO reports 23, e48754 (2022). 10. M. Zhang, A. Zhao, C. Guo, L. Guo, A combined modelling and experimental study of heat shock factor SUMOylation in response to heat shock