Post-Doctoral Training Fellow - Telomere Biology

Updated: about 1 month ago
Location: London, ENGLAND
Job Type: FullTime
Deadline: 25 Apr 2021

Closing Date: 25/04/2021, 23:55

Length of Contract: 3 years

Hours per Week: 35

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. We provided the first convincing evidence that DNA damage is the basic cause of cancer, laying the foundation for the now universally accepted idea that cancer is a genetic disease. Today, The Institute of Cancer Research (ICR) leads the world at isolating cancer-related genes and discovering new targeted drugs for personalised cancer treatment.

Under the leadership of our Chief Executive, Professor Paul Workman FRS, the ICR is ranked as the UK’s leading academic research centre. Together with our partner The Royal Marsden, we are rated in the top five cancer centres globally.

The ICR is committed to attracting, developing and retaining the best minds in the world to join us in our mission – to make the discoveries that defeat cancer.

Vacancy Description  

A postdoctoral research scientist position is available from March 2021 in the Telomere Biology Team at the Institute of Cancer Research, based in the heart of central London.

Telomeres allow eukaryotic cells to distinguish the ends of linear chromosomes from double strand breaks and protect them from repair processes and DNA damage. Telomere defects are observed in essentially all incidents of cancer and are thought to be a major driver of tumorigenesis. The Telomere Biology Team, led by Dr Max Douglas in the ICR Division of Cancer Biology, aims to understand how these fascinating structures are replicated and processed each cell division cycle, and how these steps are regulated in time and space.

We seek a postdoctoral research scientist to develop an innovative research project that will examine the molecular mechanism of telomere replication and processing steps. You will join an enthusiastic and collaborative group analysing DNA replication and the biology of telomeres using a multidisciplinary approach that employs reconstituted in vitro biochemical assays, structural biology and genetics (see for example Douglas et al, Nature 2018). You will be given opportunities to use your own initiative and to work in collaboration with others.

Applicants should possess a PhD in a biological science such as molecular cell biology, biochemistry or biophysics. Experience with in vitro biochemistry or structural biology is desirable but not essential.

Appointment will be on a Fixed Term Contract for 3 years in the first instance. The full salary scale for the post is in the range from £32,844 p.a. to £45,224 p.a. inclusive. Starting salary will be based on previous postdoctoral experience.

Please do not send your application to Dr Douglas, formal applications must be submitted online.

To apply please complete an application form, including the supporting statement section (addressing with specific examples where you meet the person specification and incl. the names and addresses of two referees) and upload your CV online.


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