What would happen if the liquid enabling life were not water, but a class of molecules with a similar melting range known as 'ionic liquids'? Ionic liquids are simply liquids made of ions usually defined as having melting temperatures below 100°C for which there are millions of possible options. Yet the charges of these ions deliver quite different physicochemical properties and can modify the 3D structure of proteins.
Our project seeks a keen researcher to use a mixture of experimental and computational techniques to unravel the underlying principles behind protein structure in different ionic liquids so that we can predictively redesign both the protein landscape and target new and renewably sourced ionic liquids for applications ranging from biosensors and 3D-printed materials to healthcare. And maybe just answer the question of what life might be like if it developed in these highly-charged environments.
We have excellent high-throughput experimental and computational facilities, enabling you to develop new screening approaches and apply machine-learning principles to solving this multi-variate puzzle. You will also have a range of opportunities to gain valuable transferrable skills (including through our doctoral college), network with international partners, and be well-set up for a role in either industry, data science or academia at the end of the programme.
Additional Funding Information
Tuition fees cover the cost of your teaching, assessment and operating University facilities such as the library, IT equipment and other support services. University fees and charges can be paid in advance and there are several methods of payment, including online payments and payment by instalment. Fees are reviewed annually and are likely to increase to take into account inflationary pressures.
The studentship is for 3 years and provides a tax-free stipend of standard UK Research Council rate (currently £18,622 for 2023/24) for the duration of the studentship plus university tuition fees.