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diagnostics. Single-cell proteomics and secretomics is on its way to make a similar groundbreaking impact on our future understanding of cells and will significantly contribute to the development of drugs and
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project supported by an Ambizione grant of the Swiss National Science Foundation , we will investigate the molecular diversity of synaptic proteomes from in-vivo brain structures (see van Oostrum et. al
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PhD student position in synapse-type specific proteome studies 100%, funded; Start date is by mutual arrangement, with the possibility to start immediately How does life emerge from molecules and
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. The candidate will focus on the characterization of chronic wounds arising from venous ulcers and perform comprehensive proteomic and metabolomic characterization of wound exudates from patients. Furthermore
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on the characterization of chronic wounds arising from venous ulcers and perform comprehensive proteomic and metabolomic characterization of wound exudates from patients. Furthermore, the candidate will demonstrate Raman
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on the data management system LabKey, to integrate data and metadata from several technology platforms at the university (sequencing, proteomics, biobanks, imaging, etc.) with other structured data generated in
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, metagenomics, metatranscriptomics, proteomics, metabolomics). Data and IT infrastructural management. The candidate supports the management, storage and submission to relevant repositories of the various data
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) and gene regulation studies (ChIP-seq, ATAC-seq, DNA variants calling), long reads sequencing, proteomics and spatial transcriptomics Set up robust and reproducible workflows to standardize analyses
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, integration and interpretation of omics data including single cell, bulkRNAseq, proteomic and clinical parameters in R and/or Python. • Excellent problem-solving skills and ability to troubleshoot technical
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include a mouse facility, high-end FACS, IT and microscopy facilities, the Life Sciences Training Facility (for gene expression and proteome profiling) and much more. The candidate is expected to have a